(noun) ; a rounded mass; as / (noun) a large pill / (noun) a soft mass of chewed food / (noun) a dose of a substance (as a drug) given intravenously / (noun) a large dose of a substance given by injection for the purpose of rapidly achieving the needed therapeutic concentration in the bloodstream / (adverb) all at once
My thoughts on this were a bolus, to use a word I owe to Denoon and that seems to have become indispensable to me.