OxyContin first sank its teeth into the poorer communities. “From a sales perspective, OxyContin had its greatest early success in rural, small town America—already full of shuttered factories and Dollar General stores,” Beth Macy wrote in Dopesick, her powerful account of opioid addiction and abuse. Within the first two years of the drug’s release, 24 percent of high school juniors in a small western Virginia town said they had tried OxyContin along with 9 percent of seventh graders.